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Large-scale Biosafety

Webinar

Large-scale Biosafety will review biosafety for work at large-scale, which the NIH rDNA Guidelines defines as >10L. The course will review Appendix K from GLSP to BSL-3 LS, with a focus on primary and secondary containment. It will review basic bioprocessing steps, such as fermentation/cell culture and purification technologies. Examples of classic and newer single use technologies will be provided. Pearls and pitfalls of the various technologies will be discussed, using various scenarios. The course will include a review of risk assessment techniques used for large scale bioprocesses and a discussion of large-scale related to vaccines, viral vectors, and recombinant proteins.

Molecular Biology 101

Webinar

Molecular Biology 101 is intended for those professionals that participate in protocol review, facilities planning, and other risk assessment activities but lack a basic understanding of molecular biology and techniques. Following this course, attendees will be able to do more than regurgitate facts and use the new understanding of the principles of molecular biology in various situations at their institution. This course will cover topics such as the chemistry of nucleic acids, DNA replication, RNA transcription, and protein translation, the Central Dogma of Biology, DNA cloning, transfection of prokaryotic and eukaryotic cells, restriction enzymes, and recombinant DNA lab methodologies (including PCR, DNA fingerprinting, sequencing, and detection protocols). While this course will not turn you into a molecular biologist, it will give you enough background information to understand the nature and manipulation of genetic material and hopefully unveil the mystery of deoxyribonucleic acid.

Q&A Infectious Substance Shipping

Webinar

Q&A Infectious Substance Shipping A distance learning opportunity August 19, 2022 12:00 – 3:00pm (CDT) Q&A Infectious Substance Shipping webinar provides an opportunity for participants to learn about recent changes to international regulations and interact with a panel of shipping experts. Regulatory experts from organizations including the DOT, InMark, and FAA have been invited along with a packaging expert from Saf-T-Pak to discuss hazardous material shipping. Participants will be afforded an opportunity to submit questions for the panel to review in advance. As many questions as possible will be discussed during the webinar. Questions not addressed will be collated, answered by the experts, and provided to all participants along with a transcript of the session.

Virus-based Gene Transfer Vectors

Webinar

Virus-based Gene Transfer Vectors is an intermediate course that will examine the molecules, processes, and techniques involved in recombinant gene expression. Participants will explore the technology of how viruses are converted into vector systems for the transfer of gene expression constructs. Common viral vector systems, including retroviruses, lentiviruses, adenoviruses, poxviruses, herpesviruses, alphaviruses, and baculoviruses will be discussed with an emphasis on the biosafety characteristics of the vectors derived from these viruses. This course is targeted for the biosafety professional who is not actively conducting laboratory research yet requires a basic understanding of recombinant DNA methodology.

1V. Animal Research for Biosafety Professionals – An Introduction

Zoom , United States

Monday, September 12, and Wednesday, September 14, 2022, from 12:30 PM - 5:00 PM CDT 1V. Animal Research for Biosafety Professionals – An Introduction Susan Harper, DVM, DACLAM, DACVPM, RBP(ABSA), NIH—Office of Animal Care and Use, Bethesda, MD Lesley Colby, DVM, DACLAM, University of Washington, Seattle, WA Animal Research has contributed to major scientific advances in biomedical, veterinary, and environmental sciences and in public health. However, these efforts often pose significant risks to the health and safety of research and facility staff due to the wide range of species, complex experimental procedures and equipment, and facility hazards that are involved. [...]

5V. Laboratory Transition: Planning for the Inevitability of Change

Zoom , United States

Thursday, September 29, 2022, from 10:00 AM - 3:00 PM CDT 5V. Laboratory Transition: Planning for the Inevitability of Change Lauren Richardson, DVM, MPH, DACVPM, Merrick & Company, Greenwood Village, CO Ryan Gregory, P.Eng, CxA, Merrick & Company, Greenwood Village, CO Aurel Tamburri, MHM, D.OHS, CRSP, University of Toronto, Toronto, Ontario, Canada Life sciences facilities are expensive and require long timelines for facility change. The last few years have emphasized the importance of adaptable, flexible solutions to accommodate changing needs for laboratory operations. Everyone has experienced the trials of transition during the global COVID-19 pandemic. A changing environment necessitates rapid [...]

3V. Articulating the Value of Your Biosafety Program

Zoom , United States

Monday, October 3 and Friday, October 7, 2022, from 10:30 AM - 3:00 PM CDT 3V. Articulating the Value of Your Biosafety Program Robert Emery, DrPH, CBSP(ABSA), University of Texas Health Science Center—Houston, Houston, TX Scott Patlovich, DrPH, CBSP(ABSA), University of Texas Health Science Center—Houston, Houston, TX Kristen King, DrPH, CBSP(ABSA), University of Texas Health Science Center—Houston, Houston, TX A recurrent challenge confronting biosafety professionals is the ability to garner necessary program resources to achieve desired goals and objectives. The basis for this difficulty is that, on a good day in the world of biosafety, “nothing happens”. The underlying challenge [...]

02. Updating Your Preparedness Toolbox for Future Outbreaks or Pandemics

Webinar

What’s coming next in the world? Do you have the tools you need to be prepared for the next outbreak or pandemic? Updating Your Preparedness Toolbox for Future Outbreaks or Pandemics is a roundtable discussion that will feature several biosafety and public health professionals. The panelists, who work across government, academia, industry, and public health, will discuss aspects of their institution’s response to emerging and reemerging pathogens and infectious disease emergencies. Lessons learned from previous emergencies will be shared. Topics will include risk assessment, communication challenges and solutions, program and policy changes, and occupational health.

ARS1V. Plant Pathology and Containment

Zoom , United States

The course will provide a background overview and illustration of how containment facilities for plant research can be designed, constructed, and operated to meet various standards and guidelines. The standards will be based on those given by US agencies though international entities will also be referenced. Principles of plant diseases and the organisms that cause them will be discussed as well as an emphasis on the pathways that pathogens may disseminate to new areas and using diagnosis for early and accurate detection. Case studies will be used to give an overview of systems that protect cropping systems from plant diseases. [...]

01. Arthropod Research, Containment, Biosafety and Beyond

Webinar

Virus-based Gene Transfer Vectors is an intermediate course that will examine the molecules, processes, and techniques involved in recombinant gene expression. Participants will explore the technology of how viruses are converted into vector systems for the transfer of gene expression constructs. Common viral vector systems, including retroviruses, lentiviruses, adenoviruses, poxviruses, herpesviruses, alphaviruses, and baculoviruses will be discussed with an emphasis on the biosafety characteristics of the vectors derived from these viruses. This course is targeted for the biosafety professional who is not actively conducting laboratory research yet requires a basic understanding of recombinant DNA methodology.

4V. BSL-3 Design and Operations: Lessons from the Trenches

Zoom , United States

Friday, February 17, 2023, from 10:00 AM - 3:00 PM CDT 4V. BSL-3 Design and Operations: Lessons from the Trenches Matt Anderson, PhD, RBP(ABSA), CBSP(ABSA), University of Nebraska—Lincoln, Lincoln, NB Many academic institutions have built Biosafety Level 3 containment laboratories over the past 15 years, anticipating these facilities to be an instrument to attract researchers and stay on the cutting edge of science. Most of these labs have been successfully operated since construction while others have become dormant due to various factors ranging from poor initial design, construction issues, engineering flaws, lack of operational staff, lack of funding for the [...]

ARS2V. Agricultural Risk Assessment

Zoom , United States

This course will cover critical differences between the “normal” laboratory risk assessment process (as outlined in the Biosafety in Microbiological and Biomedical Laboratories (BMBL)) and the more holistic agricultural risk assessment process that is required to focus on both worker health and safety as well as release to the environment. Biocontainment is a part of all risk assessment processes and it becomes critically important to delineate it as a separate goal of risk mitigation strategies when working with agriculturally important agents, as they are not often highly hazardous to humans. Therefore, these agents are seen as “safe” when, in reality, [...]

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