Resources with keywords: ebola



Guidance for Personal Protective Equipment (PPE)
CDC
1 October 2024

This guidance refers only to the following viral hemorrhagic fevers: Ebola, Marburg, Lassa, Crimean Congo Hemorrhagic Fever (CCHF), and the South American Hemorrhagic Fevers (i.e., those caused by Junin, Machupo, Chapare, Guanarito and Sabia viruses).

Establishment and application of a surrogate model for human Ebola virus disease in BSL-2 laboratory
Virologica Sinica
29 March 2024

Yang W, et al.

Highlights

  • Recombinant vesicular stomatitis virus expressing Ebola virus glycoprotein is lethal in immunocompetent Syrian hamsters.
  • The pathogenicity of VSV-EBOV/GP is species-specific, age-related, gender-associated, and challenge route-dependent.
  • Syrian hamsters develop uveitis, multi-organ failure, and severe systemic diseases resembling symptoms of human EBOV patients.
  • The model is available for anti-EBOV antibody and vaccine evaluation under BSL-2 conditions.
Preparing for another Ebola Outbreak: The impact of viral inactivation methods on commonly measured biochemistry analytes in plasma and urine
Clinical Biochemistry
17 January 2024

Zhou J, et al.
Infectious specimens containing viruses like Ebola require sample manipulation to ensure the safety of laboratory staff, which may negatively impact biochemistry test results. We evaluated the impact of viral inactivation methods on 25 biochemistry analytes in plasma, and seven biochemistry analytes in urine.

Case fatality risk among individuals vaccinated with rVSVΔG-ZEBOV-GP: a retrospective cohort analysis of patients with confirmed Ebola virus disease in the Democratic Republic of the Congo
The Lancet
7 February 2024

Coulborn R, et al
Vaccination with the Ebola vaccine significantly lowered case fatality risk vs not vaccinated.

12/11/2023: Lab Advisory: Clinical Testing Guidance for Patients with Suspected Viral Hemorrhagic Fevers
CDC / Laboratory Outreach Communication System (LOCS)
11 December 2023

While the risk of VHFs being brought into the US by travelers is very low, CDC recommends that clinical laboratories review the testing guidance in this article for ebolaviruses, marburgviruses, Crimean-Congo hemorrhagic fever virus, arenaviruses (Lassa, Lugo, and South American hemorrhagic fever viruses), and Nipah virus.

Guidance on Performing Routine Diagnostic Testing for Patients with Suspected VHFs or Other High-Consequence Disease
CDC

This guidance applies to viral hemorrhagic fevers caused by infections with:

  • Filoviruses (ebolaviruses and marburgviruses),
  • Arenaviruses [Lassa, Lujo, and South American hemorrhagic fever viruses (Guanarito virus, Sabia virus,
  • Junin virus, Chapare virus, Machupo virus)],
  • Rift Valley fever virus, and
  • Crimean Congo hemorrhagic fever virus.
Uganda declares Ebola Virus Disease outbreak
WHO
20 September 2022

WHO declares outbreak in Uganda with a rare Ebola Sudan virus.

MMWR Ebola Reports
CDC/MMWR
keywords: ebola
Infectious Substance Special Permits
US DOT
Donning Biological PPE - Ebola Patients
University of Nebraska Medical Center
keywords: ebola, PPE
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