Resources with keywords: VHF



Isolation of Diverse Simian Arteriviruses Causing Hemorrhagic Disease
CDC / Emerging Infectious Diseases
1 April 2024

Shaw TM, Dettle ST, Mejia A, Hayes JM, Simmons HA, Basu P, et al.
Genetically diverse simian arteriviruses (simarteriviruses) naturally infect geographically and phylogenetically diverse monkeys, and cross-species transmission and emergence are of considerable concern.

Establishment and application of a surrogate model for human Ebola virus disease in BSL-2 laboratory
Virologica Sinica
29 March 2024

Yang W, et al.

Highlights

  • Recombinant vesicular stomatitis virus expressing Ebola virus glycoprotein is lethal in immunocompetent Syrian hamsters.
  • The pathogenicity of VSV-EBOV/GP is species-specific, age-related, gender-associated, and challenge route-dependent.
  • Syrian hamsters develop uveitis, multi-organ failure, and severe systemic diseases resembling symptoms of human EBOV patients.
  • The model is available for anti-EBOV antibody and vaccine evaluation under BSL-2 conditions.
Preparing for another Ebola Outbreak: The impact of viral inactivation methods on commonly measured biochemistry analytes in plasma and urine
Clinical Biochemistry
17 January 2024

Zhou J, et al.
Infectious specimens containing viruses like Ebola require sample manipulation to ensure the safety of laboratory staff, which may negatively impact biochemistry test results. We evaluated the impact of viral inactivation methods on 25 biochemistry analytes in plasma, and seven biochemistry analytes in urine.

Case fatality risk among individuals vaccinated with rVSVΔG-ZEBOV-GP: a retrospective cohort analysis of patients with confirmed Ebola virus disease in the Democratic Republic of the Congo
The Lancet
7 February 2024

Coulborn R, et al
Vaccination with the Ebola vaccine significantly lowered case fatality risk vs not vaccinated.

12/11/2023: Lab Advisory: Clinical Testing Guidance for Patients with Suspected Viral Hemorrhagic Fevers
CDC / Laboratory Outreach Communication System (LOCS)
11 December 2023

While the risk of VHFs being brought into the US by travelers is very low, CDC recommends that clinical laboratories review the testing guidance in this article for ebolaviruses, marburgviruses, Crimean-Congo hemorrhagic fever virus, arenaviruses (Lassa, Lugo, and South American hemorrhagic fever viruses), and Nipah virus.

CDC Travel Alert 2 Marburg in Equatorial Guinea
CDC
keywords: Marburg, outbreak, travel, VHF
Lab Advisory: Guidance for Marburg Virus Disease Specimen Testing
CDC/LOCS
25 May 2023
keywords: Marburg, outbreak, travel, VHF
Marburg Virus Disease Outbreaks in Equatorial Guinea and Tanzania
CDC / Health Alert Network (HAN)
6 April 2023

Alert concerning two confirmed outbreaks of Marburg virus disease (MVD)—one in Equatorial Guinea and one in Tanzania.

keywords: Marburg, outbreak, VHF
Guidance for U.S. Hospitals and Clinical Laboratories on Performing Routine Diagnostic Testing for Patients with Suspected Ebola Disease
CDC

This document provides guidance for hospitals and clinical laboratories on performing routine diagnostic (non-ebolavirus) testing necessary for management and care of patients with suspected ebolavirus infection, while minimizing risk to laboratory personnel.

Outbreak of Ebola virus disease (Sudan ebolavirus) in Central Uganda
CDC/Health Alert Network
6 October 2022

The CDC is reporting a recently confirmed outbreak of Ebola virus disease (EVD) in Uganda caused by Sudan virus (species Sudan ebolavirus) to summarize CDC’s recommendations for U.S. public health departments and clinicians, case identification and testing, and clinical laboratory biosafety considerations.

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