Resources with keywords: HCW IPC
As of 18 May: 10 cases (8 lab-confirmed), 3 deaths. No confirmed U.S. Andes virus cases. Clinical laboratories advised to handle specimens from suspected HPS patients under BSL-2 enhanced precautions (Class II BSC, respirator). Andes virus is NOT a U.S. Select Agent, but laboratory directors should review biosafety risk assessments for specimen processing. Serology (IgM/IgG ELISA) and RT-PCR are diagnostic methods of choice; CDC DHCPP available for testing support.
Andes virus is the only known hantavirus capable of person-to-person transmission, documented in healthcare settings without adequate IPC. Outbreak originated aboard MV Hondius (Ushuaia, Argentina departure). Illness characterized by fever, GI symptoms, and rapid progression to ARDS and shock. Hospital workers caring for hantavirus pulmonary syndrome (HPS) patients require contact and droplet precautions at minimum; airborne precautions during aerosol-generating procedures.

