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  • Large-scale Biosafety

    Webinar

    Large-scale Biosafety will review biosafety for work at large-scale, which the NIH rDNA Guidelines defines as >10L. The course will review Appendix K from GLSP to BSL-3 LS, with a focus on primary and secondary containment. It will review basic bioprocessing steps, such as fermentation/cell culture and purification technologies. Examples of classic and newer single use technologies will be provided. Pearls and pitfalls of the various technologies will be discussed, using various scenarios. The course will include a review of risk assessment techniques used for large scale bioprocesses and a discussion of large-scale related to vaccines, viral vectors, and recombinant proteins.