Resources with keywords: ferrets
Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets
Nature Communications
20 December 2023
Halwe NJ, Hamberger L, Sehl-Ewert J, et al.
We show that bat H9N2 has high replication and transmission potential in ferrets, efficiently infects human lung explant cultures, and is able to evade antiviral inhibition by MxA in transgenic B6 mice. Together with its low antigenic similarity to the N2 of seasonal human strains, bat H9N2 fulfils key criteria for pre-pandemic IAVs.
