Resources with keywords: diagnostic failure
Human Infection with Highly Pathogenic Avian Influenza A(H5N5) Virus
New England Journal of Medicine
7 May 2026
First peer-reviewed report of H5N5 human infection in a 75-year-old immunocompromised patient. Nasal swab RT-PCR was initially negative; confirmed only via deep sequencing. This has direct implications for laboratory workers: standard influenza diagnostic assays may miss novel subtypes in immunocompromised patients. Biosafety officers should review subtype-specific testing protocols and PPE for novel subtype specimen processing.
