Resources with keywords: Creutzfeldt Jakob Disease
This article reviews the infection control guidance relative to iatrogenic transmission of CJD.
Rutala W, et al.
The recommendations in this article consider inactivation data but also use epidemiological studies of prion transmission, infectivity of human tissues, and efficacy of removing microbes by cleaning.
Bruna C, et al.
This review sought to provide an overview of proposed methods and protocols for processing surgical instruments contaminated with prions.
Belondrade M, et al.
A current limitation for validating decontamination/sterilization of surgical instruments is the lack of a rapid model permissive to human prions. The authors developed a prion detection assay based on protein misfolding cyclic amplification (PMCA) technology combined with stainless-steel wire surfaces as carriers of prions (Surf-PMCA).
McDonnell J, et al.
investigate the combination of cleaning, disinfection and/or sterilization on reducing the risk of surface prion contamination.
