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So far ABSA Office has created 5 blog entries.

Prion Toolbox: For Navigating the Challenging Field of Misfolded Proteins

Prions are misfolded proteins that defy conventional biology and are not well understood. Prions consist of proteins, lack nucleic acids, and are challenging to work with.  Human prion diseases are transmissible, progressive, and cause fatal neurodegenerative disorders. Despite rare occurrences (1-2 persons per million), prions pose considerable public health threat due to lack of pre-mortem diagnostics tests, unavailability of therapeutic and prophylactic interventions, species and strain variations, and unique propagation methods. The ABSA Emerging Infectious Diseases Committee (EIDC) presents Prion Toolbox that will enable biosafety professionals in general understanding of this elusive and complicated disease, perform risk assessment for research [...]

2024-09-20T10:15:49-05:00September 12th, 2024|

Looking for Waterborne Diseases or Fungal Diseases resources to conduct your risk assessments?

The ABSA Emerging Infectious Diseases Committee (EIDC) collated resources that will help the biosafety professional conduct risk assessments for waterborne diseases and fungal diseases. The CDC says "every year, waterborne disease causes 7 million illnesses and $3 billion in healthcare costs in the US". The Waterborne Diseases toolbox (https://absa.org/topic/waterborne/) include resources for the US and abroad, includes publications, manuals for surveillance, applicable regulations, risk mitigation, and more. Human fungal diseases are increasing in importance globally and, unfortunately, the perception of their importance to public health is much lower than is required for an effective response. Fungal pathogens have not [...]

2024-05-01T08:41:03-05:00June 30th, 2023|

Biosecurity Commentary: Hacking a Lab’s Pathogen Containment System; should this experiment have been published?

A recent article by a group of cyber-physical security experts at University of California Irvine (UCI) highlighted a potential vulnerability in negative pressure containment rooms. https://dl.acm.org/doi/10.1145/3548606.3560643 A commentary about this article was authored by George Poste and David Gillum at Arizona State University asking the question: "Should this research have been published?" https://thebulletin.org/2023/01/researchers-hacked-a-labs-pathogen-containment-system-was-it-a-good-idea-to-publish-the-results/#post-heading The authors discuss the impact of publishing lab vulnerabilities considering recent scrutiny of potential gain-of-function research and the relative lack of government oversight over this line of research.  They go on to criticize the disparity between this release of information and how the cybersecurity community has [...]

2023-03-03T12:05:49-06:00March 3rd, 2023|

Updated ABSA LAI Database include ZIKV, Macacine alphaherpesvirus 1, SARS CoV-2, and Shiga Toxin

The ABSA International Laboratory-Acquired Infection (LAI) Database has posted new entries for the following pathogens or toxins. You can search partial terms using the asterisk (*), AND, OR: 2013- Shiga Toxin from Escherichia coli O157:H7: mixing six E. coli O157:H7 strains in a soil-biochar blend Unknown time- Zika Virus; Injection of a highly concentrated live ZIKV strain into a mouse, followed by blood withdrawal and sacrifice of the mouse 2021- SARS-CoV-2; Actual cause not identified. The article speculates that the researcher took off her PPE in the wrong order, starting with the "face mask." 2021- Monkey B virus, Herpes B virus, Macacine alphaherpesvirus [...]

2022-12-06T14:32:59-06:00December 6th, 2022|

Recent Updates to the EIDC Toolboxes January 2022

The ABSA International Emerging Infectious Diseases Committee (EIDC) continues to update the toolboxes for salient infectious diseases and other relevant topics such as antimicrobial resistance. The latest updates include the following: SARS-CoV-2/COVID-19 Toolbox updates feature resources related to minimizing transmission of SARS CoV-2 from free-range animals to humans, recent peer-reviewed publications on SARS CoV-2 variants, transition from pandemic to endemic status of SARS CoV-2 transmission, COVID-19-related syndromes, CDC updates regarding isolation and quarantine timing. Lastly, the EIDC's resource titled Considerations for Handling Potential SARS-CoV-2 samples was updated to reflect the recent Federal Select Agent and Toxins Interim Rule published in [...]

2024-08-23T15:10:46-05:00January 21st, 2022|
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