Colloquium topics include:
Newly updated Lentiviral Vector Guidelines
Presented for the first time with primary author Gary Fujimoto, this program will discuss new issues associated with lentiviral and retroviral vectors along with updated recommendations for post-exposure prophylaxis. With the FDA approvals for multiple vector-based therapies, the number of individuals working with these agents is rapidly expanding. While these technologies generally involve replication-deficient agents, the potential hazards associated with transgene incorporation into one’s genome need to be conveyed to all those working with these vectors.
TB Expert Group
Mycobacterium Tuberculosis has been a leading cause of death throughout much of human history and remains so today despite 150 years of diagnostic development and nearly a century of antibiotic availability. This session will focus on current developments in epidemiology, diagnostics, and therapeutics. Case studies and a panel discussion will provide opportunities to address issues specific to occupational and research exposures.
mRNA and other Gene Transfer Platforms
Clinical trials utilize a wide array of gene transfer platforms for the delivery of therapeutic products for the treatment of a spectrum of cancers, infectious diseases, and rare disorders. In this talk, we will highlight some contemporary gene transfer platforms currently in use in the clinic and discuss biosafety and occupational health considerations when working with such products.
Malaria Case Review and Research with Humanized Mice
Updates for employees and scientists on Plasmodium species (malaria) and risk for exposure to laboratory workers. This discussion will include a case review, information on medical management plans and post exposure prophylaxis. Mosquitoes and human liver-chimeric mice are used to study the complete Plasmodium falciparum life cycle in a lab setting. This unique process leads to insights that can help develop novel means of intervention. Ashley’s work involves some specific biosafety approaches that will be discussed.
Travel Medicine & Occupational Health
Worker protection and prevention while traveling is part of an appropriate occupational medicine program for universities. This presentation will provide the research scientist with the most up to date information on travel vaccinations, malaria prophylaxis, insect bite avoidance and prevention and treatment of traveler’s diarrhea. In addition, case studies related to prevention and treatment of travel related exposures will be included.
