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04. Fundamentals of Microbiology and Infectious Disease

Webinar

Fundamentals of Microbiology and Infectious Disease is intended for those professionals who participate in protocol review, facilities planning, and any other risk assessment activities, but are unsure as to the actual nature of the disease risks of microbiological agents. Biological safety and risk assessment will not be covered in this course. The proposed topics will cover infectious agents, virulence factors, pathogenicities, host-microbe interactions, susceptibility, modes of transmission, and the changes seen in the microbial world. If you don’t know the difference between a TCID50, PFU, or ID50; or why HBV is stable in dried blood and HIV is not; or why influenza is an inhalation hazard; or why public health officials advocate flu shots each year—then this course is for you.

05. Concepts of Virology

Webinar

Concepts of Virology will briefly review gene expression in eukaryotes and examine several concepts of virology. Characteristics of different viral families will be presented as well as general replication strategies employed by different viruses. Mechanisms of viral pathogenesis and strategies for antiviral intervention will also be explored. Participants should have a familiarity with molecular biology. The course is targeted to the biosafety professional who does not actively conduct laboratory research but would like to gain a basic knowledge of virology.

11. Field Biosafety: Protecting Researchers and Communities in Wildlife Disease Investigations

Webinar

This webinar will provide comprehensive training on field biosafety, designed specifically for biosafety professionals, researchers, veterinarians, and field personnel involved in wildlife disease research. The course is structured to offer practical guidance on assessing biosafety risks in diverse field settings and effectively implementing the Field Biosafety Levels (FBSLs)—a structured framework for zoonotic disease protection. Participants will learn to critically evaluate risks, determine appropriate biosafety levels, and apply best practices in real-world scenarios. Over the two sessions, participants will be introduced to key principles of field biosafety and detailed considerations for advising researchers on potential risks. Participants will also explore the practical application of Field Biosafety Levels (FBSLs) as a proposed standardized approach to managing zoonotic risks in diverse field environments. In the final session, participants will be given a brief recap, followed by an interactive implementation practice exercise. Real-world examples, including visual aids illustrating proper and improper biosafety practices, will be reviewed. Participants will engage in active discussions, analyzing images to identify potential biosafety hazards and propose solutions. The webinar concludes with an open Q&A session.

06. Large-scale Biosafety

Webinar

Large-scale Biosafety will review biosafety for work at large-scale, which the NIH rDNA Guidelines defines as >10L. The course will review Appendix K from GLSP to BSL-3 LS, with a focus on primary and secondary containment. It will review basic bioprocessing steps, such as fermentation/cell culture and purification technologies. Examples of classic and newer single use technologies will be provided. Pearls and pitfalls of the various technologies will be discussed, using various scenarios. The course will include a review of risk assessment techniques used for large scale bioprocesses and a discussion of large-scale related to vaccines, viral vectors, and recombinant proteins.

07. Molecular Biology 101

Webinar

Molecular Biology 101 is intended for those professionals that participate in protocol review, facilities planning, and other risk assessment activities but lack a basic understanding of molecular biology and techniques. Following this course, attendees will be able to do more than regurgitate facts and use the new understanding of the principles of molecular biology in various situations at their institution. This course will cover topics such as the chemistry of nucleic acids, DNA replication, RNA transcription, and protein translation, the Central Dogma of Biology, DNA cloning, transfection of prokaryotic and eukaryotic cells, restriction enzymes, and recombinant DNA lab methodologies (including PCR, DNA fingerprinting, sequencing, and detection protocols). While this course will not turn you into a molecular biologist, it will give you enough background information to understand the nature and manipulation of genetic material and hopefully unveil the mystery of deoxyribonucleic acid.

08. Virus-based Gene Transfer Vectors

Webinar

Virus-based Gene Transfer Vectors is an intermediate course that will examine the molecules, processes, and techniques involved in recombinant gene expression. Participants will explore the technology of how viruses are converted into vector systems for the transfer of gene expression constructs. Common viral vector systems, including retroviruses, lentiviruses, adenoviruses, poxviruses, herpesviruses, alphaviruses, and baculoviruses will be discussed with an emphasis on the biosafety characteristics of the vectors derived from these viruses. This course is targeted for the biosafety professional who is not actively conducting laboratory research yet requires a basic understanding of recombinant DNA methodology.

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