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  • EBSA Conference 2026 and Preconference courses

    Bruges Meeting & Convention Centre (BMCC) Sint-Maartensbilk 1, 8000, Brugge, Belgium

    Weaving the Future of Biosafety: Networks, Heritage, and Innovation.02 June 2026, EBSA Conference 2026 and Preconference courses, Bruges and Brugge, 2 days of EBSA pre conference courses on Tuesday 2 and Wednesday 3 June 2026, 2 days of EBSA conference on Thursday 4 and Friday 5 June 2026.

  • Better Together: A Pharma & Biotech EHS Forum

    Museum of Science 1 Science Park, Boston, MA, United States

    This dynamic, one-day forum brings together EHS experts in pharma and biotech for a focused exchange on shared challenges and strategies shaping the future of EHS.

    Free
  • 03. Beat the Bite: Tick Safety for Research Teams

    Webinar

    Beat the Bite: Tick Safety for Research Teams provides research personnel with essential guidance and practical tips for safely handling ticks in a laboratory or animal research environment. Attendees will explore the tick life cycle, zoonotic pathogen transmission, key exposure risks during colony maintenance and experiments, and how to apply appropriate biosafety measures including PPE, containment, safe handling techniques, bite prevention, decontamination, tick escape responses, and post-exposure protocols.

  • UCI BSL-3 Laboratory Training

    UC Irvine BSL-3 Training Center 4600 Health Sciences Rd., Irvine, CA, United States

    BSL-3 laboratory training is a four-day intensive training for laboratory staff, managers, biosafety professionals, and individuals with direct or indirect involvement with work in high-containment. These courses are designed to prepare individuals for the basics of safely working in and around BSL-3 laboratories and includes a mixture of practical and classroom courses

  • ChABSA Annual Scientific Symposium

    Universities at Shady Grove 9630 Gudelsky Dr, Rockville, MD, United States

    Please join us for ChABSA's annual scientific symposium, featuring keynote speakers Kelly Schultz, CEO of the Maryland Tech Council, and Rebecca Bradford, SVP of ATCC Federal Solutions. The event will be held at the Universities at Shady Grove in Rockville, Maryland and broadcast virtually. For more details, please check out our website.

  • MABSA Symposium

    The Mütter Museum at The College of Physicians of Philadelphia 19 S 22nd St., Philadelphia, PA, United States

    Registration is NOW OPEN for the 38th Annual Hybrid Biosafety Symposium presented by the Mid-Atlantic Biological Safety Association Thursday, June 18, 2026 at The Mütter Museum Philadelphia, PA. Date: June 18, 2026 Time: 8 am - 5 pm Members: $50.00 in person/$25.00 virtual Non-Members: $70.00 in person/$45 virtual Students: $20.00 in person/$10.00 virtual Agenda: https://www.mabsa.org/files/documents/09a316cc-9b6f-40bf-bdf4-53485ca09d1b.pdf Registration: use the link. In-person registration ends on June 3, 2026. Virtual registration ends on June 15, 2026. No WALK INS. For more information, see https://www.mabsa.org/  

    $10 – $70
  • Principles & Practices of Biosafety®, Charlotte, NC

    Embassy Suites by Hilton Charlotte Uptown 401 E M.L.K. Jr Blvd, Charlotte, NC, United States

    Principles & Practices of Biosafety® will introduce the essential elements of biosafety and provide extensive resource lists for use after the course. Interactive exercises will be used throughout to provide hands-on experience and to encourage networking and problem-solving among participants and instructors.  Objectives At the end of the course each participant will be able to: Describe potentially hazardous biological materials, the risks associated with their use, and the means to minimize risk and to protect against or prevent release or exposure Discuss ways to provide effective technical expertise in situations involving potentially hazardous biological materials Identify, locate, and efficiently use [...]

  • BSL-3 Operations, Maintenance, and Verification Training

    UC Irvine BSL-3 Training Center 4600 Health Sciences Rd., Irvine, CA, United States

    This introductory course is a four-day training designed to certify personnel for safe entry into an operational BSL-3 laboratory. This course consists of a mixture of classroom and practical training that includes an introduction to microbiology, biosafety, risk assessment concept, BSL-3 lab characteristics, emergency management and personal protective equipment (PPE) use including procedures for donning and doffing PPE with N95 or various PAPR respirators.

  • Quarterly PHABSA Meet-Up – June

    The Quarterly Biosafety Meet-up for June will be June 26 at noon in Temple's iNEST. The meet up is for Biosafety Professionals in the Philadelphia area to network over lunch and have a space to ask work related question directly of each other instead of on the big ABSA listserv. Feel free to add anyone local to the Philadelphia Area to the TEAMS group you think would benefit from this group. If anyone has a specific topic to discuss, please bring them to the meet-up. The agenda will be finalized later.

  • 07. Large-scale Biosafety

    Webinar

    Large-scale Biosafety will review biosafety for work at large-scale, which the NIH rDNA Guidelines defines as >10L. The course will review Appendix K from GLSP to BSL-3 LS, with a focus on primary and secondary containment. It will review basic bioprocessing steps, such as fermentation/cell culture and purification technologies. Examples of classic and newer single use technologies will be provided. Pearls and pitfalls of the various technologies will be discussed, using various scenarios. The course will include a review of risk assessment techniques used for large scale bioprocesses and a discussion of large-scale related to vaccines, viral vectors, and recombinant proteins.

  • 15. Temporary Workers in Laboratories: OSHA Requirements and Best Practices

    Webinar

    Did you know that temporary workers can be found in many academic, healthcare, and industry workplaces that have laboratories? Do you have temporary workers from a staffing agency working in your institution's laboratories alongside employees? Do you know what the legal definition of a temporary worker is, and how this impacts health and safety in your workplace when a temporary worker works in your institution's laboratories? Have you ever wondered who is responsible for the health and safety of a temporary worker who works in your laboratories? These are just some of the questions that will be reviewed and answered during this one-hour webinar. This webinar is for anyone who is involved in EHS/Biosafety Programs at institutions that hire temporary workers who work alongside employees in the laboratory setting. This webinar will be led by representatives from the US Department of Labor - Occupational Safety and Health Administration (OSHA) Temporary Worker Initiative. They will provide an overview of the temporary worker health and safety requirements as well as share best practices and resources that are available to assist you. There will be time for questions at the end of the presentation.

  • 06. Molecular Biology 101

    Webinar

    Molecular Biology 101 is intended for those professionals that participate in protocol review, facilities planning, and other risk assessment activities but lack a basic understanding of molecular biology and techniques. Following this course, attendees will be able to do more than regurgitate facts and use the new understanding of the principles of molecular biology in various situations at their institution. This course will cover topics such as the chemistry of nucleic acids, DNA replication, RNA transcription, and protein translation, the Central Dogma of Biology, DNA cloning, transfection of prokaryotic and eukaryotic cells, restriction enzymes, and recombinant DNA lab methodologies (including PCR), DNA fingerprinting, sequencing, and detection protocols). While this course will not turn you into a molecular biologist, it will give you enough background information to understand the nature and manipulation of genetic material and hopefully unveil the mystery of deoxyribonucleic acid.

  • BSL-3 Laboratory Training

    UC Irvine BSL-3 Training Center 4600 Health Sciences Rd., Irvine, CA, United States

    BSL-3 laboratory training is a four-day intensive training for laboratory staff, managers, biosafety professionals, and individuals with direct or indirect involvement with work in high-containment. These courses are designed to prepare individuals for the basics of safely working in and around BSL-3 laboratories and includes a mixture of practical and classroom courses covering: Review of biosafety principles and levels Risk assessment and management Waste management Laboratory management Safety procedures Emergency management Biosafety cabinet practices and procedures Small and large spill decontamination Donning and doffing PPE Laboratory operations and preventative maintenance Data and material management Inventory and records management Biosecurity [...]

  • 22nd Annual MABioN Biosafety Hybrid Symposium

    Warwick Allerton 701 N Michigan Ave, Chicago, IL, United States

    Aug. 3-5: The MABioN Annual Symposium is a two-day conference for biosafety professionals and others involved in biosafety. Speakers and attendees have the option to participate in person or virtually. This year the symposium is co-hosted by Northwestern University and the University of Chicago. An optional half-day pre-symposium workshop on Protein Safety will be held on Monday morning. Register separately for the Monday morning workshop, which includes a break and lunch.

  • UCI BSL-3 Laboratory Training

    UC Irvine BSL-3 Training Center 4600 Health Sciences Rd., Irvine, CA, United States

    BSL-3 laboratory training is a four-day intensive training for laboratory staff, managers, biosafety professionals, and individuals with direct or indirect involvement with work in high-containment. These courses are designed to prepare individuals for the basics of safely working in and around BSL-3 laboratories and includes a mixture of practical and classroom courses covering: Review of biosafety principles and levels Risk assessment and management Waste management Laboratory management Safety procedures Emergency management Biosafety cabinet practices and procedures Small and large spill decontamination Donning and doffing PPE Laboratory operations and preventative maintenance Data and material management Inventory and records management Biosecurity

  • 10. AI‑Enabled Lab Safety: A Hands‑On Workshop for Researchers and Biosafety Professionals

    Webinar

    Artificial intelligence (AI) chatbots are emerging as practical tools to support biosafety and biosecurity programs in communication, hazard analysis, and risk assessment. This interactive two-hour webinar introduces biosafety professionals to responsible and effective use of text-based AI tools to enhance safety documentation and experimental risk evaluations. Participants will learn how to apply AI to break laboratory workflows into task-level hazards, exposure pathways, and control measures aligned with regulatory frameworks and the hierarchy of controls. The session will demonstrate how chatbots can streamline SOP development, risk narratives, incident summaries, and plain-language training materials while maintaining compliance. Emphasis is placed on prompt design strategies for producing structured, reliable outputs. Hands-on exercises guide participants in refining prompts, validating AI-generated content, and addressing biosecurity and data governance considerations. Attendees will leave with practical workflows and reusable prompt templates to integrate AI into biosafety and security operations.

  • 17. Biosafety in the Open Lab: Strategies for Shared Accountability

    Webinar

    Often seen as common place today are teams of engineers, chemists, biologists and bioinformaticians working together in the same space, using shared equipment or shared areas. Biosafety in the Open Lab is a dynamic, collaborative webinar designed for biosafety and general safety professionals, lab managers, and researchers navigating the complexities of shared, multi-user environments. Moving beyond the traditional lecture format, this session serves as a conversational forum for peer-to-peer exchange and real-time problem-solving. Rooted in proven safe work practices, our four panelists will draw on diverse institutional backgrounds and experience to facilitate a candid discussion on managing mixed-hazard spaces and overcoming the "Tragedy of the Commons." Together, we will explore hazard mitigation with a focus on administrative controls that foster shared accountability and shift laboratory mindsets toward collective responsibility. Attendees will walk away not only with a suite of practical tools and templates but with the collective wisdom of a community dedicated to shoring up institutional safety through inspiration, commiseration, and action.

  • 2026 Biosafety and Biosecurity Training Course® (BBTC)

    Hilton Fort Collins 425 West Prospect Road, Fort Collins, CO, United States

    ABSA BBTC Fort Collins August 10-14, 2026 Hilton Fort Collins Fort Collins, Colorado A WEEK-LONG COURSE COVERING ANIMAL, GENERAL, AND PLANT BIOSAFETY AND BIOSECURITY The Biosafety and Biosecurity Training Course® (BBTC) is designed for persons who are interested in the varying aspects of the responsibility of biosafety professionals. It is also suitable for persons who supervise biosafety professionals and for those who will benefit from additional knowledge of biosafety as a complement to their primary responsibilities. The weeklong training will address preparations for audits and inspections, BSL-2/BSL-3 building design and operations, clinical and public health lab biosafety, prion disease [...]

  • 08. Virus-based Gene Transfer Vectors

    Webinar

    Virus-based Gene Transfer Vectors is an intermediate course that will examine the molecules, processes, and techniques involved in recombinant gene expression. Participants will explore the technology of how viruses are converted into vector systems for the transfer of gene expression constructs. Common viral vector systems, including retroviruses, lentiviruses, adenoviruses, poxviruses, herpesviruses, alphaviruses, and baculoviruses will be discussed with an emphasis on the biosafety characteristics of the vectors derived from these viruses. This course is targeted for the biosafety professional who is not actively conducting laboratory research yet requires a basic understanding of recombinant DNA methodology.

  • XVIII International Symposium on Biosafety and Biosecurity (SIBB 2026)

    Universidad de Monterrey Av. Ignacio Morones Prieto 4500-Pte, Zona Valle Poniente, Monterrey Nuevo León, San Pedro Garza García, Mexico

    The Mexican Biosafety Association (AMEXBIO) invites you to be part of this important international event that will bring together specialists, researchers, and professionals in biosafety and biosecurity. The XVIII International Symposium on Biosafety and Biosecurity (SIBB 2026), taking place August 18–22, 2026, at the ESTOA Building of the University of Monterrey (UDEM) in Monterrey, Mexico. Co-organized with the Center of Excellence in Medical Sciences and Innovation of the UDEM School of Medicine, SIBB is the leading regional event in biosafety, biosecurity, and biological risk management. The symposium brings together experts and professionals from across Latin America and beyond, including [...]

  • 16. Introduction to Animal Research for Biosafety Professionals

    Webinar

    Animal Research has contributed to major scientific advances in biomedical, veterinary, environmental, and public health science, but presents unique safety challenges and significant risks due to diverse species, complex procedures, and facility hazards. Balancing optimal worker safety and animal welfare with research objectives yields the best results but requires a solid understanding of how animal programs are managed and an ability to identify and mitigate inherent risks. This course provides a thorough introduction to routine hazards commonly encountered in animal programs that utilize rodents, small animals, nonhuman primates, aquatics, and agricultural species, with a primary focus on identifying and managing biological, chemical, radiological, and physical hazards. Topics include assessment and management of animal program hazards; universal regulations, guidelines, and quality standards that apply to animal research; duties and responsibilities of key program personnel; local oversight systems; best practices that enhance the quality of animal care; and strategies for biosafety professionals to develop and maintain effective partnerships with program staff and institutional animal care and use committee members. Opportunities will be provided to apply new knowledge and skills through interactive group activities and problem-solving sessions. The instructors are experienced laboratory animal veterinarians who are actively involved in management, oversight, and evaluation of animal care and use programs. The primary target audience for this course are biosafety and general safety professionals with limited experience in the animal research environment.

  • 1V. ISO35001: A Stepwise Process to Assess and Improve Biorisk Management Program

    Webinar

    August 21, August 24-25, and August 27-28, 2026, 11:00 am – 12:40 pm CDT, In 2019, ISO published a new biorisk management standard that many biomedical research laboratories all over the world are adopting. This workshop will provide presentations, facilitated discussions, and tools to introduce concepts related to biosecurity and biosafety (biorisk) management systems. Attendees will gain a deep understanding of biorisk management (BRM) systems and learn to apply the ISO 35001 framework as a strategic planning tool. The course guides participants in mapping their current systems to the ISO standard, identifying gaps, and prioritizing improvements to enhance biosafety and biosecurity practices. Using the ISO 35001 as a planning and mapping tool, will enable institutions to effectively identify, assess, control, and monitor the laboratory biosafety and biosecurity risks associated with hazardous biological materials using the concept of continual improvement through the PDCA (Plan-Do-Check-Act) principle.

  • 2V. Host Pathogen Interactions for Biosafety Professionals

    Webinar

    September 1 and September 3, 2026 - The course is intended to introduce biosafety professionals to host-pathogen interactions by focusing on fundamentals of immunology, microbiology and their interplay as they pertain to biosafety risk assessments utilizing instructional videos, case studies, established lab acquired infections and publications. Information from this course can assist biosafety professionals assess risks from microbiological research including potential effects of genetic modifications on virulence and infectivity of pathogens, susceptibility of hosts in in-vitro and in-vivo models for IBC review, assessing impact to the wellbeing of research animal hosts for IACUC review, as well as the occupational safety and occupational health of research personnel.

  • 11. Enhancing Biosafety Training with Generative AI: Multimedia Tools, Workflows, and Best Practices

    Webinar

    Enhancing Biosafety Training with Generative AI: Multimedia Tools, Workflows, and Best Practices is a practical, application focused course designed for biosafety and biosecurity professionals who develop or deliver training and want to incorporate generative AI to make their materials clearer, faster to build, and more engaging. This session goes beyond introductory AI concepts to show exactly how image, audio, and video generation tools can support the creation of effective biosafety training modules. Attendees will explore free and low cost AI tools capable of generating lab specific visuals, infographics, audio, and short instructional video clips. Instructors will compare the strengths of tools such as Copilot, ChatGPT, Gemini, and other emerging options, and demonstrate how each can be applied to biosafety training.

  • 3V. IATA Infectious Substance Shipping Certification

    Webinar

    September 9, 11, 14, 16 and 18 - This course provides essential training for individuals seeking IATA certification for infectious substance shipping. Designed for participants with some prior experience in handling or shipping infectious substances who may not have been certified within the past three years, the course is delivered through five 100-minute online sessions. Each session is followed by homework assignments that reinforce practical skills such as classifying, marking, labeling, packaging, and completing documentation for various infectious substance shipments (Category A, Category B, Exempt Patient Specimens). These assignments replace traditional classroom activities and are required for successful course completion. This course is suitable for personnel responsible for packaging, marking, and labeling shipments of all categories of infectious substances, including dry ice and liquid nitrogen. To earn a certificate and course credit, participants must complete all assignments and pass (80% or better) a written exam administered at the conclusion of the course.

  • 12. Accidents to Actions: Lessons from Laboratory Acquired Infections

    Webinar

    This course describes the resources currently available to provide data on 3,962 Laboratory-acquired infections (LAIs) published between 1979 and 2025 that occurred in clinical, teaching, veterinary laboratories, field studies, and industrial vaccine production. Case studies will highlight some of the challenges for exposure prevention in each setting to show how LAI data can support your biosafety program.

  •  2026 Canadian Biosafety Symposium

    Delta Hotels Winnipeg 350 St. Mary's Avenue, Winnipeg, MB, Canada

    The Canadian Association for Biological Safety/L’Association Canadienne pour la Sécurité Biologique (CABS-ACSB) is happy to present the Canadian Biosafety Symposium! Join us in Winnipeg, MB from September 21-23, 2026 for Canada’s annual event for biosafety professionals and personnel involved in biosafety and/or biocontainment facilities. The Canadian Biosafety Symposium will feature presentations on an array of biosafety topics, including emergency management for labs, building a biosafety culture, biosafety and public health, emerging and re-emerging diseases, laboratory acquired infections, ergonomics and safety, biowaste management and disinfection, regulations, airflow, ventilation, design and biosafety, animal issues, audits and inspections, occupational health and surveillance. It will be a unique opportunity for the biosafety community to learn and share knowledge with colleagues from across Canada and other countries.

  • 14. Toxin Science and Safety

    Webinar

    Toxin Science and Safety will provide a basis for the biosafety professional who does not conduct research with these agents but requires a basic understanding of biological toxins and venoms. Since these agents can have such drastic pharmacological effects, they are of great interest to the biomedical research community. An increasing number of research and industrial laboratories are using some of these agents as laboratory reagents. In addition, there are a number of venomous vertebrate and invertebrate species that may be studied in a research environment and can present unique safety considerations. This introductory course will also provide laboratorians working with or contemplating work with these agents with additional foundational knowledge and recommended best practices. The webinar will include interactive case history and risk assessment exercises to apply some of information described in this course.

  • 4V. Refresher IATA Shipping Certification

    Webinar

    September 30 & October 2 - This course is intended for those who are already experienced dangerous goods shippers. Professionals who wish to participate in this course must have completed an IATA Dangerous Goods certification course in the past 3 years. This refresher course updates participants on U.S. and international regulations affecting infectious substance shipping. It includes a brief review of regulations, shipper responsibilities, and the nine hazard classes, plus in-depth guidance on classification (Category A, Category B, and exempt materials) and requirements for packaging, marking, and labeling shipments—including those with dry ice or liquid nitrogen. Attendees will complete hands-on exercises, including marking and labeling packages, preparing shipper’s declarations and air waybills, and filling out required documentation. The course concludes with a review and certification test, requiring a minimum score of 80% to pass. Note that IATA certification is issued by the employer.

  • 69th Annual Biosafety and Biosecurity Hybrid Conference

    Arthur R. Outlaw Mobile Convention Center 1 South Water Street, Mobile, AL, United States

      October 10-14, 2026 Mobile Convention Center Mobile, Alabama Intensive professional development courses to educate and inspire Three full days of state-of-the-art keynotes, papers, and panels highlighting best practices and hands-on skills crucial for today’s biosafety and biosecurity professionals In-person exhibits showcasing the latest in laboratory biosafety and biosecurity products and services Invaluable networking opportunities to share and learn from other biosafety and biosecurity professionals The ABSA International Conference is the largest biosafety and biosecurity conference in the world! The conference will provide solutions to tackle your most challenging issues, present fascinating case studies, and showcase the latest developments [...]

  • 5V. Keeping it Going: Maintaining and Improving a Select Agent Program Over the Long Term

    Webinar

    October 22 & 29: Keeping a select agent program going can be difficult, especially in the face of ever-changing regulatory requirements and limited resources. Established procedures may suddenly become unacceptable, interrupting research and frustrating laboratorians. Likewise, a single unexpected adverse event can put an entire program at risk. Being prepared to deal with such changes and events is critical to maintaining a robust program. Anticipating future challenges can be even more advantageous, elevating a program from good to great. A proactive approach can minimize the impact of new requirements and reduce duration and frequency of crises sparked by sudden, unexpected requirements or events. This course will explore strategies for maintaining and improving an existing program, including how to anticipate and respond to new requirements. The focus will be on U.S. select agent requirements, although a small section on comparable requirements in the international community will be included. Strategies will be based on the instructors’ experience with their program with additional input solicited from class attendees during open discussions. Topics will include select agent program history; effective oversight; efficiently meeting ongoing requirements; reporting, responding to, and analyzing incidents; suitability program case studies; inactivation requirements, including “failure” investigation; and inspection preparation and response. The course will consist of topical presentations followed by group discussions aimed at facilitating application of presented strategies to attendees’ individual programs and providing a platform to capitalize on attendees’ collective experience.

  • Strategic Biocontainment Laboratory Planning and Operations Workshop

    CABS-ACSB and Merrick are pleased to co-present the Strategic Biocontainment Laboratory Planning and Operations Workshop. This comprehensive, hands-on workshop is designed for professionals involved in the planning, renovation, operation, and management of high-containment laboratories and research facilities. Participants will gain an in-depth understanding of the critical elements required to establish and sustain a secure, efficient, and compliant biocontainment facility. Through interactive discussions, case studies, real-world scenarios, and practical exercises, this course will cover: Biocontainment Fundamentals – A historical perspective, key design considerations, and core biosafety and biosecurity principles. Facility Planning & Design – Space allocation, workflow optimization, sustainability, and environmental impact mitigation. Regulatory [...]

  • 6V. Institutional Infectious Substance Shipping Program Assessment and Development

    Webinar

    November 9-13: This course is tailored for individuals responsible for establishing and overseeing infectious substance shipping programs within their facilities. This webinar series aims to assist institutions in developing robust shipping programs tailored to their needs. Course elements include: training; written policies; written descriptions of program plans; transport and shipping specific SOPs; safety and security plans; emergency response plans; logistics and supplies; carrier selection and support; MOUs and authorizations; access control and personnel assurance. The instructor will provide a detailed and comprehensive shipping program assessment and implementation guidance document. Attendees will receive an introduction to this document and step-by-step guidance on its completion. By completing the assessment document, attendees will conduct a thorough review to identify areas for improving existing shipping programs. This interactive, instructor led, web-based training will invite attendees to share examples of how these elements are addressed at their own institution.

  • International High Containment Operations and Maintenance Workshop

    University of Saskatchewan (USask) Saskatoon, Saskatchewan, Canada

    The University of Saskatchewan’s Vaccine and Infectious Disease Organization (VIDO) and the Canadian Association for Biological Safety/L'Association Canadienne Pour la Sécurité Biologique (CABS-ACSB) and Merrick Canada ULC are pleased to co-present the International High Containment Operations and Maintenance Workshop. This workshop addresses the increasing needs of facility operators, maintenance and operations staff for training in relevant aspects of biocontainment facilities and fills a critical need within the operations and maintenance community. The focus of this workshop is operational-based, not research based. This four day course allows participants to gain hands-on experience in some of the special containment and facility support areas (CL3 and CL3-Ag) of the International Vaccine Centre (InterVac), Canada's newest and largest CL3-Ag facility.

  • 7V. We Built the BSL-3… Now What? Operational Management, Sustainability, and Risk-Based Decision Making for High-Containment Laboratories

    Webinar

    November 19: High-containment laboratories play a critical role in public health preparedness, infectious disease research, and diagnostic response. However, constructing a Biosafety Level 3 (BSL-3) laboratory is only the first step; ensuring it is safe, sustainable, and compliant in operation presents significant technical, operational, and organizational challenges. Many institutions struggle with maintaining complex containment systems, implementing robust biosafety programs, and sustaining competent personnel and operational procedures over time. This course provides a practical framework for the operation, management, and sustainability of BSL-3 laboratories. Attendees will explore the operational components required to maintain high-containment facilities, including governance structures, risk management systems, operational procedures, infrastructure and engineering controls, preventive maintenance programs, and emergency preparedness strategies. Emphasis will be placed on integrating engineering controls, administrative controls, and biosafety practices into a coherent biorisk management approach aligned with international guidance and best practices. The course also examines common institutional challenges encountered in high-containment laboratories, including infrastructure failures, gaps in operational planning, insufficient maintenance strategies, and misalignment between laboratory design and operational capabilities. Attendees will learn how to evaluate these risks and implement practical solutions to improve laboratory performance and safety. Through case studies, operational examples, and scenario-based discussions, attendees will analyze real-world challenges related to the management of BSL-3 laboratories and explore strategies to strengthen institutional governance, improve operational resilience, and ensure sustainable laboratory performance.