Pox Viruses Toolbox

Delaney KP, Sanchez T, Hannah M, et al.

On-demand recording: Alaskapox Virus: An Emerging Animal-to-Human Infectious Disease?

Levy V, Branzuela A, Hsieh K, et al.
The first reported clade Ib MPXV infection in the Americas was identified via electronic laboratory reporting in California in a U.S. traveler who returned from East Africa.

On November 18, 2024, the U.S. Centers for Disease Control and Prevention (CDC) issued a Health Alert Network (HAN) Health Advisory about the first case of clade I mpox diagnosed in the United States.

The high proportion of children with suspected mpox reported in the current outbreak is likely due to a number of factors, including spread within and between close households, younger population demographics in impacted countries, misdiagnosis of other diseases (such as measles), poor sanitary conditions, limited access to health services, and a high level of food insecurity and malnutrition.

Gigante CM, Takakuwa J, McGrath D, et al.
Tecovirimat is the first-line drug for treatment of orthopoxvirus infection (e.g., smallpox and mpox). Viral mutations that render the drug ineffective can develop during treatment.

These are technical reports intended for scientific audiences.

Cash-Goldwasser S, Labuda SM, McCormick DW, et al.

Hagan LM, Beeson A, Hughes S, et al.

Webinar

Includes information for public health veterinarians and animal health officials

Yinda C, Morris DH, Fischer RJ, et al.
The findings suggest that, because virus stability is sufficient to support environmental MPXV transmission in healthcare settings, exposure and dose-response will be limiting factors for those transmission routes

Rao AK, Petersen BW, Whitehill F, et al.

Minhaj FS, Ogale YP, Whitehill F, et al.

These recommendations are intended for healthcare settings. 

Includes aboratory biosafety guidelines, testing, reporting procedures, use of PPE, specimen collection, packaging and transport, etc.

Mendoza R, Petras JK, Jenkins P, et al.

Choi Y, Jeon E, Kim T, Choi S, Moon SM, Song K, et al.
This report includes occupational exposure of MPOX to HCW

Caldas JP, Valdoleiros SR, Rebelo S, Tavares M.
This report includes an occupational needlestick injury from a pustule

This is a Health Alert Network (HAN) Health Update to provide additional information about the ongoing outbreak of clade I monkeypox virus (MPXV), the virus that causes mpox, in Central and Eastern Africa

Field EN, McCarty E, Saady D, et al.
During 2022, a global outbreak of mpox resulted primarily from human-to-human contact. The Virginia Department of Health (Richmond, VA, USA) implemented a contact tracing and symptom monitoring system for residents exposed to monkeypox virus, assessed their risk for infection, and offered interventions as needed.

CDC’s National Wastewater Surveillance System (NWSS) program collects and displays wastewater data from communities across the United States.

This notice is to notify clinicians and health departments about the occurrence, geographic spread, and sexually associated human-to-human transmission of Clade I Monkeypox virus (MPXV) in the Democratic Republic of the Congo.

Miller MJ, Cash-Goldwasser S, Marx GE, et al.

Total confirmed monkeypox/orthopoxvirus cases

Yinda C, Morris DH, Fischer RJ, et al.
The findings suggest that, because virus stability is sufficient to support environmental MPXV transmission in healthcare settings, exposure and dose-response will be limiting factors for those transmission routes

Worldwide, there have been no reports of transmission of monkeypox virus through blood transfusion and the risk of transfusion-transmission remains theoretical.

These data will contribute to understanding the spread of the Monkeypox virus and can contribute to predicting increases in testing demand and planning for potential supply chain issues for reagents and other testing materials.

Puenpa J, Intharasongkroh D, Vongpunsawad S, et al.
In Thailand, platelet product from a blood donor was transfused to a recipient who had dengue. Two days later, the donor was confirmed to have monkeypox virus infection. Monkeypox virus DNA was undetectable in recipient specimens up to 2 weeks after transfusion. The recipient remained asymptomatic at 4 weeks of monitoring.

Delaney KP, Sanchez T, Hannah M, et al.

Rao AK, Schrodt CA, Minhaj FS, et al.

Rao AK, Petersen BW, Whitehill F, et al.