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1V. Personnel Security in Laboratory Biosecurity Programs

Webinar

Personnel security is comprised of security measures focused on people and behaviors rather than typical physical barriers approaches. Personnel security can be thought as the "administrative controls" in any advanced security program. This course will teach administration, management, and researchers the basic principles of threat assessment and introduce participants to the role of comprehensive personnel security in a laboratory biosecurity programs. The course is intended to give participants a basic tool-kit that will allow them to implement successful comprehensive insider threat mitigation strategies using personnel security approaches at their home institutes and to convey concepts in personnel security to their colleagues. Participants will be presented with relevant case studies in order to learn about relevant threats in the biomedical and health sectors. Participants will learn about all aspects of personnel security including: suitability, reliability, peer and self reporting strategies, threat assessment, OPSEC, INFOSEC, and an introduction to elicitation, manipulation and surveillance awareness. These concepts will be put in to practice in interactive, live role-playing scenarios that include interview tactics, deception detection elicitation and surveillance detection. Regulatory issues relevant to implementation of personnel security management programs, in particular changes to the Select Agent Regulations pertaining to Tier 1 agents, will also be discussed.

3V. Using the Incident Command System for Responding to Biosecurity Incidents

Webinar

The Incident Command System (ICS) is the national gold standard for responding to any size incident in the United States. President George W. Bush mandated its use for all Federal Agencies and strongly recommended its use at all levels of government and within private organizations. The authors of this course have a significant amount of ICS experience, including the highest level of qualification in ICS: Type 1 Incident Commander. They have successfully used ICS in real-life laboratory incidents and Biosecurity exercises. The instructors intend to give the participants an overview of ICS and enough information to incorporate the system into their plans, training, and exercises. This will enable participants to begin maximizing response effectiveness and efficiency during a real laboratory incident.

2V. Tactical Implementation of Biosecurity Principles: An Advanced, Scenario-Driven Course on Risk and Threat Management Programs

Webinar

A distinguishing factor between security and biosecurity programs is the fact that biosecurity programs are focused on assets that are biological in nature. This brings forth unique distinctions in implementing risk- and threat-based approaches to prevent the release, loss, or theft of these assets. This advanced workshop will challenge attendees to fully analyze a single biosecurity driven scenario through a series of risk and threat management decision-making. Participants will learn the principles of biosecurity, which set it apart from traditional security, by applying tactical methodology to analysis of a real-world biosecurity case study. The outcomes of this intensive course will be identification of biosecurity-specific risk and threats, their corresponding prioritization against a mitigation plan, approaches for blending these inputs for comprehensive biorisk management, and finally, an integrated biosecurity plan. Participants will leave the course with tools that will be applicable to their host institutions for future engagements building effective integrated biosecurity plans against scenarios.

07. Fundamentals of Microbiology and Infectious Disease

Webinar

Fundamentals of Microbiology and Infectious Disease is intended for those professionals that participate in protocol review, facilities planning, and any other risk assessment activities, but are unsure as to the actual nature of the disease risks of microbiological agents. Biological safety and risk assessment will not be covered in this course. The proposed topics will cover infectious agents, virulence factors, pathogenicities, host-microbe interactions, susceptibility, modes of transmission, and the changes seen in the microbial world. If you don’t know the difference between a TCID50, PFU, or ID50; or why HBV is stable in dried blood and HIV is not; or why influenza is an inhalation hazard; or why public health officials advocate flu shots each year—then this course is for you.

4V. Using One Health to Advance Biosecurity

Webinar

Agricultural biosecurity is a critical component of the One Health concept. It includes various strategies designed to safeguard the health and welfare of agriculturally important animals, the environment, and society in general by preventing infections and their spread among these species, humans, and nontarget species, including wildlife. Increased movement of live animals and their products, as well as the growing trend towards intensification and expansion of animal production systems, represents a significant risk to food supply chains, public health, and the economy due to the possible emergence and spread of exotic animal pests and pathogens, zoonotic diseases, and foodborne agents. Effective management and control of these challenging and complex risks requires application of core principles and cohesive strategies that emphasize sustainability through improved husbandry and health management practices.

06. Working with Highly Pathogenic Avian Influenza Virus (HPAIV)

Webinar

Highly pathogenic avian influenza virus (HPAIV) has recently become widespread globally in animals. Human infections are rare but are reported consistently. Therefore, work with HPAIV may encompass a wide variety of activities including lab-based research, animal work, field studies, and handling of positive diagnostic specimens. The goal of this workshop is to enable the audience to understand the basics of HPAIV, the risk associated with handling the virus or positive samples, and mitigations for handling it. An introduction to the basic biology of HPAIV including a brief description of pathobiology including modes of transmission and exposure routes among different species. A summary of what is known about transmission of the virus to and from wild birds. What is known about transmission from avian species to mammals will be covered from both a virus, exposure route, and disease pathogenesis perspective. Biosafety and biosecurity for handing HPAIV in the lab, animal research and field specimens will be described.

08. Concepts of Virology

Webinar

Concepts of Virology will briefly review gene expression in eukaryotes and examine several concepts of virology. Characteristics of different viral families will be presented as well as general replication strategies employed by different viruses. Mechanisms of viral pathogenesis and strategies for antiviral intervention will also be explored. Participants should have a familiarity with molecular biology. The course is targeted to the biosafety professional who does not actively conduct laboratory research but would like to gain a basic knowledge of virology.

17. Export Compliance for the Biosafety Professional

Webinar

Export Compliance for the Biosafety Professional is designed to help biosafety officers and other professionals understand how U.S. export control laws and regulations intersect with the roles and responsibilities of a biosafety administrator. The webinar will discuss the regulatory framework governing exports from the United States, how to navigate export compliance challenges in academic and medical research environments, and best practices for handling biological exports while maintaining safety and security. 

14. APHIS 101: Arthropod and Plant Research Permits

Webinar

APHIS 101: Arthropod and Plant Research Permits is a webinar for those that work with plant pathogens, arthropods, or with genetically modified plants and insects. This course will provide participants with an overview of APHIS (Animal Plant Health Inspection Services) eFile including BRS (Biotechnology Regulatory Services), PPQ (Plant Protection and Quarantine), and VS (Veterinary Services) permitting. It will also review EPA (Environmental Protection Agency) labeling and wildlife permits and address intrastate and interstate movement of permitted organisms. The course will offer various scenarios and interactive exercises that show the process of applying for and acquiring permits. Participants will be guided through permit strategies.

13. Animal Handler Risk Assessment

Webinar

This introductory webinar will provide an overview of the hazards associated with animal work and focus on the questions that should be asked in a risk assessment to elucidate the information needed to build a complete risk assessment profile for work conducted with animals and with animal derived tissues and specimens. The webinar will cover strategies for implementing the risk assessment, including how and when to involve other specialists, and integrating the process into the overall occupational health program. Circumstances where additional information is needed to complete the risk assessment will be identified; such situations will require follow-up interviews and in some cases site visits by the biosafety professional. Translation of the risk assessment into recommendations for risk mitigation will be discussed.

15. Q&A Infectious Substance Shipping

Webinar

Q&A Infectious Substance Shipping webinar provides an opportunity for participants to learn about recent changes to international regulations and interact with a panel of shipping experts. Regulatory experts from organizations to be determined and have been invited along with a packaging expert from Saf-T-Pak/Labelmaster to discuss hazardous material shipping. Participants will be afforded an opportunity to submit questions for the panel to review in advance. As many questions as possible will be discussed during the webinar. Questions not addressed will be collated, answered by the experts, and provided to all participants along with a transcript of the session.

09. Large-scale Biosafety

Webinar

Large-scale Biosafety will review biosafety for work at large-scale, which the NIH rDNA Guidelines defines as >10L. The course will review Appendix K from GLSP to BSL-3 LS, with a focus on primary and secondary containment. It will review basic bioprocessing steps, such as fermentation/cell culture and purification technologies. Examples of classic and newer single use technologies will be provided. Pearls and pitfalls of the various technologies will be discussed, using various scenarios. The course will include a review of risk assessment techniques used for large scale bioprocesses and a discussion of large-scale related to vaccines, viral vectors, and recombinant proteins.

10. Molecular Biology 101

Webinar

Molecular Biology 101 is intended for those professionals that participate in protocol review, facilities planning, and other risk assessment activities but lack a basic understanding of molecular biology and techniques. Following this course, attendees will be able to do more than regurgitate facts and use the new understanding of the principles of molecular biology in various situations at their institution. This course will cover topics such as the chemistry of nucleic acids, DNA replication, RNA transcription, and protein translation, the Central Dogma of Biology, DNA cloning, transfection of prokaryotic and eukaryotic cells, restriction enzymes, and recombinant DNA lab methodologies (including PCR, DNA fingerprinting, sequencing, and detection protocols). While this course will not turn you into a molecular biologist, it will give you enough background information to understand the nature and manipulation of genetic material and hopefully unveil the mystery of deoxyribonucleic acid.

11. Virus-based Gene Transfer Vectors

Webinar

Virus-based Gene Transfer Vectors is an intermediate course that will examine the molecules, processes, and techniques involved in recombinant gene expression. Participants will explore the technology of how viruses are converted into vector systems for the transfer of gene expression constructs. Common viral vector systems, including retroviruses, lentiviruses, adenoviruses, poxviruses, herpesviruses, alphaviruses, and baculoviruses will be discussed with an emphasis on the biosafety characteristics of the vectors derived from these viruses. This course is targeted for the biosafety professional who is not actively conducting laboratory research yet requires a basic understanding of recombinant DNA methodology.


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